| Atg1 | 丝/苏氨酸蛋白激酶,与Atg13和Atg17形成复合物,参与自噬的起始过程. | Protein serine/threonine kinase, forms a complex with Atg13 and Atg17, and participates in autophagy initiation. |
| Atg2 | 外周膜蛋白,参与自噬囊泡的形成,Atg9在自噬泡组装位点（PAS）及线粒体间的穿梭循环. | Peripheral membrane protein required for autophagic vesicle formation, involved in cycling of Atg9 from the PAS to the mitochondria. |
| Atg3 | E2交联酶,参与Atg8与磷脂酰乙醇胺（PE）交联形成Atg8-PE的过程. | E2-like enzyme, plays a role in formation of Atg8-phosphatidylethanolamine conjugates. |
| Atg4 | 半胱氨酸蛋白酶,通过剪切碳末端的半胱氨酸残基或去除PE调节Atg8蛋白的脂化修饰. | Cysteine protease, cleaves the carboxy terminal arginine residue of Atg8, or PE from Atg8-PE conjugate. |
| Atg5 | 多以Atg12-Atg5偶联的形式存在于细胞中,Atg5- Atg12-Atg16复合物的组成部分,参与自噬体的形成. | Mostly exists as Atg12-Atg5 conjugates, part of the Atg12-Atg5- Atg16 complex, essential for autophagosome formation. |
| Atg6 | III类PI3K复合物I和II的组成部分,复合物I参与自噬过程,复合物II参与液泡蛋白分选（VPS）过程. | Subunit of PI3K complexes I and II; Complex I is essential in autophagy and Complex II is required for vacuolar protein sorting. |
| Atg7 | E1活化酶,介导Atg12与Atg5,以及Atg8与PE的偶联. | E1-like activating enzyme, mediates the conjugation of Atg12 with Atg5 and Atg8 with PE. |
| Atg8 | 泛素样蛋白,与PE偶联,调控自噬体形成过程中自噬泡的延伸. | Ubiquitin-like protein, conjugates with PE, involving in phagophore expansion during autophagosome formation. |
| Atg9 | 跨膜蛋白,在PAS及其他细胞内结构间穿梭循环. | Transmembrane protein cycles between the PAS and other cytosolic punctate structures. |
| Atg10 | E2交联酶,介导Atg12-Atg5复合物的形成. | E2-like conjugating enzyme; mediates formation of the Atg12-Atg5 conjugate. |
| Atg11 | 接头蛋白,参与过氧化物酶体自噬及Cvt通路. | Adapter protein for pexophagy and the Cvt targeting pathway. |
| Atg12 | 泛素样蛋白,与Atg5偶联形成Atg12-Atg5,Atg5-Atg12- Atg16复合物的组成部分. | Ubiquitin-like protein, conjugated to Atg5 to form a complex, part of the Atg5-Atg12-Atg16 complex. |
| Atg13 | Atg1复合物的调控亚基,其磷酸化水平负向调节Atg1的激酶活性. | Regulatory subunit of the Atg1p signaling complex, its phosphorylation levels negatively regulates Atg1 kinase activity. |
| Atg14 | III类PI3K复合物I 的组成部分,负责将复合物I定位到PAS. | Subunit of class III PI3K complex I, targets complex I to the PAS. |
| Atg15 | 一种跨膜脂酶,参与自噬囊泡的降解,释放其内容物. | Transmembrane lipase, required for the degradation of the autophagic vesicle. |
| Atg16 | 参与形成Atg5-Atg12-Atg16复合物,结合至细胞膜并定位于前自噬体结构. | Part of Atg5-Atg12-Atg16 complex, binds to membranes and localizes to the pre-autophagosomal structure. |
| Atg17 | 支架蛋白,调节Atg1 蛋白的激酶活性,并参与PAS蛋白定位组装. | Scaffold protein, stimulates Atg1 kinase activity, and acts as a scaffold for the other ATG proteins during PAS organization. |
| Atg18 | 磷脂酰肌醇结合蛋白,在自噬及Cvt途径的囊泡形成过程中发挥重要作用. | Phosphoinositide binding protein; required for vesicle formation in autophagy and the Cvt pathway. |
| | 待续 |
| | 续表1 |
| Atg19 | Cvt途径中的受体蛋白,运送底物蛋白至PAS. | Receptor protein for the Cvt pathway, delivers cargo proteins to the PAS. |
| Atg20 | 分选连接蛋白,参与Cvt途径,能与PI3P结合. | Sorting nexin family member, participates in the Cvt pathway, has a Phox homology domain that binds PI3P. |
| Atg21 | 磷脂酰肌醇结合蛋白,参与Cvt途径的囊泡形成过程. | Phosphoinositide binding protein, required for vesicle formation in the Cvt pathway. |
| Atg22 | 液泡上的内在膜蛋白,参与液泡中氨基酸的释放. | Vacuolar integral membrane protein required for efflux of amino acid. |
| Atg23 | 外周膜蛋白,与Atg9及Atg27形成复合物,在PAS及非PAS区域穿梭循环. | Peripheral membrane protein, forms a complex with Atg9 and Atg27, and cycles between PAS and non-PAS cytoplasmic sites. |
| Atg24 | 分选连接蛋白,与PI3P结合,参与Cvt途径. | Sorting nexin family member, contains a PX phosphoinositide-binding domain, play a role in Cvt pathway. |
| Atg25 | Coiled-coil蛋白,参与汉逊酵母的过氧化物酶体自噬过程. | Coiled-coil protein, function during macropexophagy in Hansenula Polymorpha. |
| Atg26 | 甾醇葡萄糖基转移酶,参与毕赤酵母自噬过程. | Sterol glucosyltransferase, involved in the Pichia pastoris autophagy progress. |
| Atg27 | I型膜蛋白,参与自噬及Cvt途径,可能参与转运膜结构转运到PAS的过程. | Type I membrane protein involved in autophagy and the Cvt pathway, may be involved in membrane delivery to the PAS. |
| Atg28 | Coiled-coil蛋白,参与毕赤酵母过氧化物酶体自噬过程. | Coiled-coil protein, function during pexophagy in Pichia pastoris. |
| Atg29 | 参与形成Atg17-Atg29-Atg31复合物,募集其他ATG蛋白至自噬体前体结构. | Part of Atg17-Atg29-Atg31 complex, recruits other ATG proteins to the pre-autophagosomal structure. |
| Atg30 | 过氧化物酶体的受体,参与过氧化物酶体自噬过程,不参与巨自噬及Cvt途径. | Peroxisome receptor, required for pexophagy, but not for the Cvt or autophagy pathways. |
| Atg31 | 参与形成Atg17-Atg29-Atg31复合物,参与自噬体的形成过程. | Part of Atg17-Atg29-Atg31 complex, required for autophagosome formation. |
| Atg32 | 线粒体外膜蛋白,募集Atg11及Atg8至线粒体表面起始线粒体自噬. | Mitochondrial outer membrane protein, recruits the Atg11 and the Atg8 to the mitochondrial surface to initiate mitophagy. |
| Atg33 | 线粒体自噬特异性蛋白,不参与其他自噬过程. | Mitochondrial mitophagy-specific protein, not required for other types of autophagy. |
| Atg34 | Atg19的旁系同源蛋白,参与饥饿诱导的选择性自噬过程. | Paralog of Atg19, receptor protein involved in selective autophagy during starvation. |
| Atg35 | 参与毕赤酵母过氧化物酶体自噬过程,可以定位在细胞核中. | Founction during pexophagy in Pichia pastoris, the first known nuclear protein required for the Atg pathway in yeasts. |
| Atg36 | 与Atg8及Atg11相互作用,参与过氧化物酶体自噬过程. | Required for pexophagy, interacts with Atg8 and Atg11. |
| Atg37 | 酰基辅酶A结合蛋白,调节过氧化物酶体自噬中自噬泡的形成. | Conserved acyl-CoA-binding protein, is required for pexophagy at the stage of phagophore formation. |
| Atg38 | III类PI3K复合物I中的同型二聚体亚基,维系PI3K复合物I的活性,可参与到巨自噬过程. | Homodimeric subunit of PI3K complex I, required for the integrity of the active PI3K complex I and macroautophagy. |
| Atg39 | 参与内质网和细胞核降解的自噬受体. | Autophagy receptor with a role in degradation of the ER and nucleus. |
| Atg40 | 参与内质网降解的自噬受体. | Autophagy receptor with a role in ER degradation. |