基于网络药理学和分子对接技术探讨冬虫夏草治疗肾纤维化的潜在作用机制
|
|
范卫锋,邹园生,李文佳,李皓翔,汪小东,梅全喜,钱正明
|
Analyses of potential mechanism of Chinese cordyceps in treating renal fibrosis based on network pharmacology and molecular docking
|
|
FAN Wei-Feng,ZOU Yuan-Sheng,LI Wen-Jia,LI Hao-Xiang,WANG Xiao-Dong,MEI Quan-Xi,QIAN Zheng-Ming
|
|
表3 分子对接结果
|
Table 3 Binding energy of molecular docking (KJ/mol)
|
|
成分
Compounds | MAPK1
(6SLG) | MAPK3
(2ZOQ) | PIK3CA
(6OAC) | PIK3CB
(4BFR) | PIK3CD
(5T8F) | RELA
(1VJ7) | | 金色酰胺醇酯Aurantiamide acetate | -5.296 | -5.744 | -4.536 | -8.860 | -5.161 | -5.095 | | 啤酒甾醇Cerevisterol | -4.861 | -4.042 | -3.514 | -5.135 | -5.892 | -3.084 | | 酒渣碱Flazin | -6.969 | -7.181 | -6.336 | -6.671 | -7.224 | -5.095 | | 花生四烯酸Arachidonic acid | -3.999 | -3.406 | -4.431 | -6.135 | -5.877 | -3.754 | | 11,14-二十碳二烯酸11,14-Eicosadienoic acid | -3.691 | -2.309 | -3.856 | -5.499 | -4.568 | -1.646 |
|
|
|