基于网络药理学和分子对接技术探讨冬虫夏草治疗肾纤维化的潜在作用机制

范卫锋,邹园生,李文佳,李皓翔,汪小东,梅全喜,钱正明

Analyses of potential mechanism of Chinese cordyceps in treating renal fibrosis based on network pharmacology and molecular docking

FAN Wei-Feng,ZOU Yuan-Sheng,LI Wen-Jia,LI Hao-Xiang,WANG Xiao-Dong,MEI Quan-Xi,QIAN Zheng-Ming

图6 冬虫夏草活性成分与靶点的分子对接图 A：金色酰胺醇酯-PIK3CB;B：啤酒甾醇-PIK3CD;C：酒渣碱-PIK3CD;D：花生四烯酸-PIK3CB;E：11,14-二十碳二烯酸-PIK3CB

Fig. 6 Molecular docking diagram of active compounds in Chinese cordyceps and targets. A: Aurantiamide acetate-PIK3CB; B: Cerevisterol-PIK3CD; C: Flazin-PIK3CD; D: Arachidonic acid-PIK3CB; E: 11,14-Eicosadienoic acid-PIK3CB.