牛樟芝多糖对HepG2细胞酒精性氧化损伤的保护作用

杨彬君,冯彩玲,吴岩斌,易骏,吴锦忠,吴建国

Protective effect of Taiwanofungus camphoratus polysaccharides on alcohol-induced oxidative injury in HepG2 cells

YANG Bin-Jun,FENG Cai-Ling,WU Yan-Bin,YI Jun,WU Jin-Zhong,WU Jian-Guo

表2 WEE和CP对5.5%酒精诱导HepG2细胞损伤生化指标的影响

Table 2 The effects of WEE and CP on the biochemical indices of HepG2 cell injure induced by 5.5% alcohol

组别 Group 谷丙转氨酶 ALT (U/L) 谷草转氨酶 AST (U/L) 超氧化物歧化酶 SOD (U/mg) 过氧化氢酶 CAT (U/mg) 空白对照 Blank control 5.48±0.93 7.55±0.82 199.61±9.69 15.92±0.80 模型 Model set 23.11±1.77## 10.94±1.51## 141.21±5.33## 11.52±0.76## WEE (μg/mL) 100 12.76±1.09** 9.27±1.30 145.03±7.44 12.54±0.69 200 9.35±0.70** 8.36±1.15* 168.27±15.17* 13.24±0.80* 400 6.40±0.86** 8.06±0.91** 169.41± 9.61** 14.21±0.72** CP (μg/mL) 100 12.39±0.57** 10.13±1.06 133.09±7.48 11.95±0.53 200 11.43±0.92** 9.07±0.75* 148.43±2.61 12.07±0.44* 400 9.70±1.39** 7.13±0.84** 168.71±11.83** 13.24±0.24**