比较代谢组学分析桑枝屑栽培对瓦尼桑黄代谢的影响

宋吉玲,闫静,陆娜,程俊文,周祖法,林佳瑶,王伟科,袁卫东

Analysis of impact of mulberry sawdust on the metabolism of Sanghuangporus vaninii based on comparative metabolomics

SONG Jiling,YAN Jing,LU Na,CHENG Junwen,ZHOU Zufa,LIN Jiayao,WANG Weike,YUAN Weidong

图9 差异代谢物KEGG富集网络图 注释到代谢通路的具体代谢物，硫胺素代谢：pos_1247：一磷酸硫胺素;neg_385：l-酪氨酸;pos_1414：磷酸吡哆醛;neg_995：甘氨酸;neg_986：5-(2-羟乙基)-4-甲基噻唑;pos_1143：NAD. 果糖和甘露糖代谢：neg_281：山梨糖;neg_993：2-(α-d-甘露糖)-3-磷酸甘油酸酯;neg_1366：d-甘露醇-1-磷酸;neg_311：l-岩藻糖. 糖基磷脂酰肌醇(GPI)锚生物合成：neg_870：1-磷脂酰-d-肌醇;neg_436：O-磷酸乙醇胺. 磷酸戊糖途径：neg_878：1,5-二磷酸核糖;neg_107：糠醛;pos_944：葡糖酸内酯;pos_1602：2-脱氢-d-葡萄糖酸;neg_1327：d-葡萄糖酸-1,5-内酯;neg_825：β-d-葡萄糖-6-磷酸;pos_232：2-脱氧核糖. 嘧啶代谢：pos_2042：l-氢化乳清酸;pos_1443：尿嘧啶;pos_1084：尿苷;neg_994：dUDP;neg_977：l-谷氨酰胺;neg_280：甲基丙二酸;neg_1013：尿嘧啶核苷酸;neg_222：dUMP;neg_534：假尿苷三磷酸;neg_331：脱氧尿苷;pos_945：乳清酸核苷酸

Fig. 9 KEGG enrichment network diagram of differential metabolites. Specific metabolites annotated to metabolic pathways. Thiamine metabolism: pos_1247: Thiamine monophosphate; neg_385: l-tyrosine; pos_1414: Pyridoxal 5′-phosphate; neg_995: Glycine; neg_986: 5-(2-hydroxyethyl)-4-methylthiazole; pos_1143: NAD. Fructose and mannose metabolism: neg_281: l-sorbose; neg_993: 2-(alpha-d-mannosyl)-3-phosphoglycerate; neg_1366: d-mannitol 1-phosphate; neg_311: l-fucose. Glycosylphosphatidylinositol (GPI)-anchor biosynthesis: neg_870: Phosphatidyl-d-inositol; neg_436: O-phosphoethanolamine. Pentose phosphate pathway: neg_878: Ribose 1,5-bisphosphate; neg_107: Furfural; pos_944: Gluconolactone; pos_1602: 2-dehydro-d-gluconate; neg_1327: d-glucono-1,5-lactone; neg_825: Beta-d-glucose 6-phosphate; pos_232: 2-deoxy-d-Ribose. Pyrimidine metabolism: pos_2042: l-dihydroorotate; pos_1443: Uracil; pos_1084: Uridine; neg_994: dUDP; neg_977: l-glutamine; neg_280: Methylmalonic acid; neg_1013: Uridine 5′-monophosphate; neg_222: dUMP; neg_534: Pseudouridine 5′-phosphate; neg_331: Deoxyuridine; pos_945: Orotidylic acid.